Institute of Graduate Studies and Research

Bioengineering (PhD)

Duration 5 Years

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About
Curriculum
Entry Requirements
Fees & Scholarships

About the Program

The Ph.D. in Bioengineering program prepares students to become leading researchers, educators, and entrepreneurs. The program provides knowledge breadth in engineering and the biological sciences as well as student’s personal area of interest. Program aims to educate academics who will be able to contribute to the national and international projects related to bioengineering.

Scientists of bioengineering have made countless revolutionary advances that have changed the way people live. Now, it is time to combine engineering principles with biology. Research in bioengineering will strengthen our understanding of the basic principles of biological and environmental systems, create novel solutions to today's health and environmental problems, and open new pathways for technological innovation.

Education Opportunities

By learning to advance through both engineering and biological knowledge, it is anticipated that the graduates will be well-prepared for leadership careers in academia and industry related to biotechnology, medicine, and other emerging fields based on biological technology. The curriculum consists of technical elective courses, a seminar and a thesis. These courses are chosen by the students in consultation with their course advisors and can be selected from the offered Ph.D. courses on bioprocess engineering, nanotechnology, biological materials, drug delivery systems, cancer biology and biotechnology. Research methods course is offered to the students in order to improve their research knowledge and skills. A supervisor who is expert in their field is assigned for each student to assisting the student in preparing the seminar and to design an action plan of a study so that a comprehensive degree program is offered with a focus on a particular bioengineering area. Students carry out their experiments in modern laboratories equipped with high-technology tools and equipment.

Career Areas

The Ph.D. program is ideal for professionals seeking greater depth in several areas of bioengineering who wish to enhance their foundation for being a researcher, lecturer or manager in designing biological technologies and in other fields related to bioengineering..

Biotechnology Research Center (BRC) was established to develop international projects and accelerate research and development facilities in our country. The activities of this center are in the fields of cancer biology, microbiology and environmental sciences. BRC carries out projects with international partners such as Imperial College and University of Oxford. Bioengineering Ph.D. students will be supported to take part in these projects and improve themselves. By this way, they would be highly experienced scientists and would also help our society in the fields of cancer, microbiology and environment.

Contact

Institute of Graduate Studies and Research
Graduate Sciences and Education Center, GE106
Tel: +90 392 671 1111 Extension: 2776
Institute E-mail: ciu-institute@ciu.edu.tr

Compulsory Courses

First Semester

SEMINAR

Course code

BIOE690

Credit

Theoretical

Practical

Ects

ELECTIVE

Course code

BIOE6X1

Credit

Theoretical

Practical

Ects

ELECTIVE

Course code

BIOE6X2

Credit

Theoretical

Practical

Ects

ELECTIVE

Course code

BIOE6X3

Credit

Theoretical

Practical

Ects

ELECTIVE

Course code

BIOE6X4

Credit

Theoretical

Practical

Ects

Second Semester

THESIS

Course code

BIOE600

Credit

Theoretical

Practical

Ects

160

QUALIFICATION EXAM

Course code

BIOE650

Credit

Theoretical

Practical

Ects

ELECTIVE

Course code

BIOE6X5

Credit

Theoretical

Practical

Ects

ELECTIVE

Course code

BIOE6X6

Credit

Theoretical

Practical

Ects

Philosophy of Science

Course code

PHIL601

Credit

Theoretical

Practical

Ects

This course will follow three main paths: Firstly it will introduce philosophy to doctoral students. The meaning of philosophy, its scope, its sub-branches and its different schools will be the subject topic of the first weeks. Then the course will focus on the relation of philosophy with the sources of knowledge and different sciences. Here, Rationalism, Empiricism and Intuitionism will be covered during the following weeks. In the remaining weeks the course will concentrate on philosophy of science and scientific ethics. Logical positivism, paradigm changes, falsificationism, the questions of “what is science”, “what is pseudo-science?”, “what is the relation between theory and reality?” are amongst topics that will be covered. Finally, the course will concentrate on ethical theories and will particularly cover scientific ethics.

Elective Courses

BIOMATERIALS

Course code

BIOE616

Credit

Theoretical

Practical

Ects

THERMODYNAMICS

Course code

ENRE301

Credit

Theoretical

Practical

Ects

BIOPROCESS ENGINEERING

Course code

BIOE308

Credit

Theoretical

Practical

Ects

BIONANOTECHNOLOGY

Course code

BIOE622

Credit

Theoretical

Practical

Ects

CANCER BIOLOGY

Course code

BIOE628

Credit

Theoretical

Practical

Ects

SPECIAL TOPICS IN BIOENGINEERING II

Course code

BIOE633

Credit

Theoretical

Practical

Ects

BIOMEDICAL ENGINEERING AND INSTRUMENTATION

Course code

BIOE303

Credit

Theoretical

Practical

Ects

TECHNIQUES IN MOLECULAR BIOENGINEERING

Course code

BIOE601

Credit

Theoretical

Practical

Ects

TECHNIQUES IN TISSUE CULTURE AND CELLULAR BIOENGINEERING

Course code

BIOE602

Credit

Theoretical

Practical

Ects

GENETIC ENGINEERING

Course code

BIOE610

Credit

Theoretical

Practical

Ects

PHYSIOLOGY FOR ENGINEERS

Course code

BIOE613

Credit

Theoretical

Practical

Ects

METABOLISM AND CELLULAR ADAPTATION

Course code

BIOE636

Credit

Theoretical

Practical

Ects

BIOSENSORS

Course code

BIOE607

Credit

Theoretical

Practical

Ects

ADVANCED RESEARCH METHODS FOR ENGINEERING

Course code

ENGI660

Credit

Theoretical

Practical

Ects

This course covers data analysis using statistical methods, e.g., descriptive and multivariate analysis. Furthermore, the course covers the topics of correlation, sampling, estimation, and hypotheses testing. The logic and key assumptions underpinning the multivariate ordinary least squares regression model will be given together with more advanced subjects such as the analysis of time series and panel data analysis. The emphasis will be on achieving a smooth transition between theory, model definition, and outcome presentation. It will illustrate several methods of data analysis, presenting the findings of analyses (for example, visually, using graphics, tables, and text), and understanding their meaning. Students will gain hands-on experience with the techniques discussed in this course by applying them to various datasets using statistical software

BIOSEPERATIONS

Course code

BIOE606

Credit

Theoretical

Practical

Ects

STATISTICAL COMPUTER APPLICATIONS FOR SOCIAL SCIENCES

Course code

STAT602

Credit

Theoretical

Practical

Ects

Entering the data collected to the computer, organizing and getting data ready for statistical analyses; normal distribution and sampling distribution of the mean; establishing confidence intervals; writing research questions, research hypotheses, null hypotheses; hypothesis testing. Descriptive statistics: Measures of central tendency and position measurements (arithmetic mean, median, peak, percentile and quartile); measures of variability (distribution width, variance, standard deviation); display of data. Inferential statistics: t-test applications (single-sample t-test, independent samples t-test, dependent samples t-test), analysis of variance applications (one-way ANOVA, two-way ANOVA, MANOVA, ANCOVA); correlations (Pearson and Spearman correlation coefficients), partial correlation; multiple linear regression; exploratory and confirmatory factor analyses; reliability; non-parametric tests (Wilcoxon signed rank test, Mann-Whitney U test, Kruskal-Wallis test, Chi-Square tests); interpreting and writing results of analyses.

FERMENTATION MICROBIOLOGY

Course code

BIOE631

Credit

Theoretical

Practical

Ects

RESEARCH METHODS

Course code

EMNT525

Credit

Theoretical

Practical

Ects

This course is designed to be a background pass to graduate studies. The ability to formulate a research question, finding the data relevant to research questions, analyze those data, and presentation of research findings are skills that will be acquired through this course. Scientific thinking skills and methods of research, using library and online archives, experimental design, and presenting quantitative data are modules covered within the scope of this course. Scientific communication, writing research proposals, scientific reporting and thesis writing are also supported. Conference presentations, time management in research projects, ethical issues, plagiarism and skills of working in a group and networking are also highlighted throughout the semester.

SPECIAL TOPICS IN BIOENGINEERING I

Course code

BIOE632

Credit

Theoretical

Practical

Ects

Philosophy of Science

Course code

PHIL601

Credit

Theoretical

Practical

Ects

GENERAL PHYSICS I

Course code

PHY101

Credit

Theoretical

Practical

Ects

MOLECULAR APPROACHES IN PHARMACEUTICAL SCIENCES

Course code

PSCI611

Credit

Theoretical

Practical

Ects

The research methods course introduces student to principal and modern concepts of research. This course helps the student to build an analytical and systematic link between theory and practice. Students will be able to develop skills in carrying out literature search using electronic databases, catalogues and print media using proper referencing methods, conduct preliminary literature review, familiarize in experimental methods as well as practice analyzing and interpreting data. Students are expected to recognise the significance of technological innovations, professional and ethical responsibilities in research. Students will be able to analyze and present research results in writing and in oral presentations as well as understanding scope and limits of qualitative and qualitative research methodologies.

SPECIAL TOPICS IN ENVIRONMENTAL ENGINEERING

Course code

ENVE633

Credit

Theoretical

Practical

Ects

Various advanced level topics will be covered on environmental engineering, according to the need of students and interest of the instructor.

TECHNIQUES IN TISSUE CULTURE AND CELLULAR BIOENGINEERING

Course code

BIOE502

Credit

Theoretical

Practical

Ects

This is a course will begin with introducing practical skills for the isolation of animals cells for in vitro studies, maintenance of animal cells in vitro, manipulation of animal cells in vitro, and application of molecular techniques to in vitro situations. This course also designed to bridge cell biology with engineering. At the completion of this course, the students should be able to: Discuss the molecular and cellular basis of life from an engineering perspective, identify crucial molecular parameters involved in cellular events measure and manipulate molecular parameters experimentally, apply engineering principles, concepts, and mathematical modelling in studying molecular parameters, cell structure, function, and appropriately capture the salient features of the cellular phenomena. In addition, the students should be able to manipulate the behaviour of biological cells, examine structure-function relationship and explore and criticize the existing and emerging technologies that exploit and extend our knowledge of molecular and cell biology.

BIOSENSORS

Course code

BIOE507

Credit

Theoretical

Practical

Ects

This course will cover the principles, technologies, methods and applications of biosensors and bioinstrumentation. The objective of this course is to link engineering principles to understanding of biosystems in sensors and bioelectronics. It will provide the student with detail of methods and procedures used in the design, fabrication and application of biosensors and bioelectronic devices. The fundamentals of measurement science are applied to optical, electrochemical, mass, and pressure signal transduction. Upon successful completion of this course, students are expected to be able to explain biosensing and transducing techniques, design and construct biosensors instrumentation.

IMMUNOLOGY

Course code

BIOE611

Credit

Theoretical

Practical

Ects

ECOLOGY

Course code

BIOE626

Credit

Theoretical

Practical

Ects

BIOTECHNOLOGY

Course code

BIOE635

Credit

Theoretical

Practical

Ects

MICROBIOLOGY

Course code

BIOE623

Credit

Theoretical

Practical

Ects

BIOTECHNOLOGY

Course code

BIOE535

Credit

Theoretical

Practical

Ects

TISSUE ENGINEERING

Course code

BIOE612

Credit

Theoretical

Practical

Ects

GENERAL BIOLOGY FOR ENGINEERS

Course code

BIOE112

Credit

Theoretical

Practical

Ects

MÜHENDİSLİK İÇİN BİYOLOJİ

ADVANCED PHARMACEUTICAL AND BIOMEDICAL SCIENCES

Course code

PSCI602

Credit

Theoretical

Practical

Ects

This multidisciplinary, integrated course, introduces the students to the modern concepts and applications used in biomedical and pharmaceutical sciences. This course, focused on principles of carrying out laboratory based, molecular, basic research, covers main techniques and technologies used in pharmaceutical and biomedical sciences as well as providing information on their daily use in research labs. Students are expected to learn and effectively used several search portals to access prominent papers in the field and read/reference/present the discussed techniques/discoveries effectively. They are also expected to write and present research proposals covering the discussed techniques and topics as well as evaluating their and their peers’ work critically.

ADVANCED TECHNIQUES OF ENVIRONMENTAL ENGINEERING ANALYSIS

Course code

ENVE528

Credit

Theoretical

Practical

Ects

Aims to understand the working principles of modern analytical instruments, and how they can be used to solve analytical problems encountered in environmental engineering. Includes optical methods, ultra violet, visible, infrared, X ray absorption, emission and flame spectroscopy, selective ion electrodes, mass spectroscopy, gas and liquid chromatography theory and applications, total organic carbon analyzer, electrical separation methods. Laboratory experiments.

ADVANCED PHARMACOGNOSY I

Course code

PRCO503

Credit

Theoretical

Practical

Ects

The plant and animal kingdom as source of drugs, General methods associated with the phytochemical investigation pf herbal products; Extraction of plant Material, separation and isolation of constituents: Sublimation, distillation, Fractional liberation, fractional chrystallization, Adsorbsion chromatography, Partition chromatagraphy, High performance liquid chromatography (HPLC), ThinLayer Chromatography(TLC), Gas-Liquid chromatography, Gel filtration chromatography, Electrochromatography, Basic metabolic pathways and the origin of secondary metabolites; Enzymes, Photosynthesis, Carbohydrate utilization, Glycosides, Fats and Fatty acids,, Aromatic biosynthesis, The shikimic acid pathway, The acetate hypothesis Amino acids biosynthesis, Peptides and proteins, Isoprenoid compounds The mevalonic acid pathway, Secondary metabolites, Stress compounds, Discovering new lead compounds in pharmaceutical research and development. Phytochemical variation within a species.

TOXIC AND HALLUCINOGENIC PLANTS

Course code

PRCO505

Credit

Theoretical

Practical

Ects

MORPHOLOGICAL AND MICROSCOPIC DEFINITIONS OF VEGETABLE DRUGS

Course code

PRCO512

Credit

Theoretical

Practical

Ects

COMPUTER AIDED DATA ANALYSIS

Course code

EMNT515

Credit

Theoretical

Practical

Ects

Following a general introduction, the qualitative and quantitative data, their systems of collection and analysis are given to the students. Regression and correlation analysis concepts. Case studies and solutions by using relevant software such as SPSS. Quality control concepts with respect to data analysis. Students will be able to manage qualitative data in an efficient and accessible manner, develop a qualitative data analysis plan, choose and apply different inductive and deductive approaches to coding appropriate to the data type and the context in which results will be used, employ and write analytical memos to aid in interpretation of qualitative data, understand the basic functions of computer-aided qualitative data analysis software, present qualitative findings in different settings using formats appropriate for different audiences.

ADVANCED ANAEROBIC TREATMENT

Course code

ENVE609

Credit

Theoretical

Practical

Ects

ADVANCED TOPICS IN AIR POLLUTION

Course code

ENVE611

Credit

Theoretical

Practical

Ects

Meteorology for modeling and control of air pollution; the physical and thermodynamic properties of the atmosphere, equations of motion, hydrostatic equation, continuity equation, Geostrophic approximation, geopotential height, thermal wind, baroclinic and barotropic atmosphere, atmospheric stability and inversion. Air pollution concentration models; fixed-box models, diffusion models. Primary particulate control. Control of sulfur oxides and nitrogen oxides.

ADVANCED TOPICS IN BIOTECHNOLOGY

Course code

ENVE614

Credit

Theoretical

Practical

Ects

Advanced level topics in biotechnology. Different topics will be covered according to the need of students and interest of the instructor.

ADVANCED TOPICS IN BIOTECHNOLOGY

Course code

ENVS614

Credit

Theoretical

Practical

Ects

Advanced level topics in biotechnology. Different topics will be covered according to the need of students and interest of the instructor.

BIONANOTECHNOLOGY

Course code

BIOE522

Credit

Theoretical

Practical

Ects

FERMENTATION MICROBIOLOGY

Course code

BIOE531

Credit

Theoretical

Practical

Ects

CALCULUS I

Course code

MAT101

Credit

Theoretical

Practical

Ects

LABORATORY APPLICATIONS IN ENVIRONMENTAL AND BIO TECHNOLOGIES

Course code

ENVE640

Credit

Theoretical

Practical

Ects

STATISTICAL METHODS IN BIO&ENVIRONMENTAL SCIENCES

Course code

ENVS641

Credit

Theoretical

Practical

Ects

The main topics of this course are: numerical summary statistics, graphical summary techniques, probability theory, probability distributions, mathematical expectation, special probability distributions (bernoulli, binom, poisson), probability density functions (gama, exponantial, chi-square), linear regression and correlation, excell and spss applications, sampling distributions, hypothesis testing.

STATISTICAL METHODS IN BIO&ENVIRONMENTAL SCIENCES

Course code

ENVE641

Credit

Theoretical

Practical

Ects

ADVANCED PHARMACOGNOSY-II

Course code

PRCO504

Credit

Theoretical

Practical

Ects

ADVANCED PHARMACOGNOSY-II

CALCULUS-I

Course code

MATH101

Credit

Theoretical

Practical

Ects

Calculus-I provides the methods of differential and integral calculus with applications in geometry, physics and engineering. Students in this course will learn how to use mathematical language needed for applying the concepts of calculus to numerous applications in science and engineering such as identifying types of functions, graph of functions, evaluating limit of functions, limit of elementary functions (polynomial, trigonometric, logarithmic, exponential,…), methods to solve the undefined limits (L’Hopitals Rule), continuous functions, evaluating derivative of functions, definition of derivative, derivative of elementary functions, derivative of product of two functions and division of functions, applications of derivative, evaluate integrals of functions, definition of the integral, integral of elementary functions, substitution method, integration by parts, integral of rational functions, application of the integral (finding the area) .

MEDICINAL SIGNIFICANCE OF NATURAL PRODUCTS

Course code

PSCI607

Credit

Theoretical

Practical

Ects

The natural products obtained from plants, microorganisms, algae etc. and their biomedical uses will be studied in this course. A discussion of bioassay-directed screening, the isolation, structure determination, biosynthesis, partial synthesis and total chemical synthesis of organic natural products of medicinal significance. Examples of the classes of compounds to be considered include steroid hormones, cardiac glycosides, alkaloids, antibiotics, terpenes, and the like. Different plants used in pharmaceutical sciences and biomedical sciences as well as the potential of not yet studied plants will be evaluated. Extraction methods aimed at extracting the active ingredients and the methods used to test these ingredients on eukaryotic and prokaryotic cells will be discussed.

POISONOUS PLANTS

Course code

PSCI628

Credit

Theoretical

Practical

Ects

In this course, the important poisonous plants used in the Mediterranean countries and their characteristics will be introduced. Information will be given about the regions where the plants are distributed, their characteristics and the points that should be taken into consideration in their use for therapeutic purposes. The Family and the genus of the species like Digitalis ferruginea (Scrophulariaceae), Atropa belladonnae (Solanaceae), Aconitum napellus (Ranunculaceae), Colchicum autumnale (Liliaceae), Matricaria chamomilla and Echinacea purpurea (Asteraceae), which of them have ethnobotaniccal use to threat various diseases. Plant collection, drying, storage and how to use the plants will be described. Due to the toxic compounds they contain, information will be given about the issues needs to be taken into consideration during use. In addition, literature review of poisonous plants with medicinal use will be explained.

TRNC
International

Students who are interested in pursuing advanced graduate studies leading to a master’s, doctoral degree or professional doctorate degree for the Fall and Spring semesters every year. Applicants can directly apply online to our graduate programs using the application portal.

TRNC Applicants- Required documents:

Bachelor’s and Master’s Degree Diploma
Bachelor’s and Master’s Degree transcripts for each completed academic term/year.
Documents to prove English proficiency for English language departments,
Scanned copy of passport or identity card.

Click for detailed admission requirements information.

Students who are interested in pursuing advanced graduate studies leading to a master’s, doctoral degree, or professional doctorate degree for the Fall and Spring semesters every year. Applicants can directly apply online to our graduate programs using the application portal.

International Applicants- Required documents:

A valid Bachelor’s Degree and transcripts for each completed academic term/year.
A valid Master’s Degree and transcripts for each completed academic term/year.
Evidence of English Language competence: TOEFL (65 IBT) or IELTS (5.5). Students without these documents will take the CIU English proficiency exam on campus following arrival.
Scanned copy of international passport/birth certificate
CV
Ph.D. research proposal
Fully completed and signed CIU Rules and Regulations document (which can be downloaded during the online application)

Click for detailed admission requirements information.

Scholarships
Fees

Cyprus International University provides academic scholarships for its students as an incentive for success, with most students benefiting from 50%, 75% or 100% scholarships or discounted tuition fees. Click for more information.

Tuition Fees are determined at the beginning of each academic year. Candidate students who are entitled to enroll in CIU can learn their fees in line with the Tuition Fee Calculation system.